Annelise Erpenbeck began her Otterbein women’s soccer career with tons of potential and a great desire to improve as a goalkeeper. She was willing to do the work and contribute whenever needed, but one class ahead of her stood Katie Chrien, the program's most successful goalkeeper to that point. Erpenbeck put in work for three seasons, improving and stepping in when needed. She couldn't have been needed more than when she was called upon to play 80 minutes in the NCAA Sweet 16 as a junior after Chrien went down with an injury. Annelise came into the game with no warm-up, finished regulation and anchored the team through two overtime periods without allowing a goal. She also made a save in ensuing shootout before Otterbein fell just short.

The fall of 2006 would prove to be the season Erpenbeck prepared for. As the team struggled through injuries to 14 players and constant changes in the lineup, Annelise's play remained constant. By the end of the season, she had tallied 14 shutouts, tying the school and conference record for a single season at that time. The team also defended its OAC regular-season title but fell short in a shootout in the league’s tournament championship, despite another save from Erpenbeck.

Her contributions on the field, coupled with an outstanding performance in the classroom as an athletic training major, garnered Annelise a 2006 CoSIDA Academic All-America Award. She later went on to earn a master's degree in Physician Assistant Studies at the Medical University of South Carolina. She now works in the Emergency Department at Springs Memorial Hospital in SC.